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Cervical Cancer

Cervical neoplasia risk in southern Chinese women not linked to HLA-B alleles

Published in Women's Health Weekly, April 17th, 2006

Cervical neoplasia risk in southern Chinese women was not linked to HLA-B alleles.

"A population-based study was conducted on 256 southern Chinese with cervical intraepithelial neoplasia grade III (CIN III) or invasive cervical cancer (ICC) and on 258 controls to examine the associations between HLA-B alleles, infection with high-risk human papillomaviruses (HPVs) and the development of cervical neoplasia. HLA-B15 was found to be protective for CIN III/ICC overall (pcorrected =.003), and for HPV52-positive CIN III/ICC (pcorrected =.003)," scientists in the People's Republic of China reported.

"A marginal protective effect of B15...

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