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Diabetes Prevention

Hormone therapy may have antidiabetic effect but may also increase risk of heart disease

Published in Women's Health Weekly, April 24th, 2006

Decreased fasting glucose and proinsulin levels in current hormone replacement therapy (HRT) use suggest a potential antidiabetes effect of HRT.

"One putative benefit of hormone replacement therapy (HRT) is a reduced risk of diabetes or reduced fasting glucose level," noted scientists at the University of California at San Diego. "We report the association of HRT with proinsulin, insulin, and fasting and postchallenge glucose levels in older adults."

D.J. Kim and E. Barrett-Connor explained, "Current HRT use was validated and cross-sectionally compared with diabetes-related variables in 785 women without diabetes by history or glucose tolerance test....

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