Cervical Cancer Vaccine
Immunosuppression limits efficacy of anticancer vaccines in late-stage cervical cancer
Published in Women's Health Weekly, May 1st, 2006
Researchers in the United States and Italy conducted a study "to evaluate the potential of human papillomavirus (HPV) type 16 and 18 E7 antigen-loaded autologous dendritic cells (DC) as a therapeutic cellular vaccine in a case series of cervical cancer patients harboring recurrent/metastatic disease refractory to standard treatment modalities."
"Autologous monocyte-derived DC were pulsed with recombinant HPV16 E7 or HPV18 E7 oncoproteins and administered to four cervical cancer patients," said Alessandro D. Santin and collaborators at the...
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