Mental Health
Estrogen may be protective against schizophrenia by inhibitive effect on buspirone
Published in Women's Health Weekly, May 8th, 2006
Researchers at Australia's Mental Health Research Institute of Victoria reported, "The sex steroid hormone, estrogen, has been proposed to be protective against schizophrenia. This study examined the effects of estrogen treatment on modulation of prepulse inhibition (PPI) by the serotonin-1A (5-HT1A) receptor partial agonist, buspirone."
"PPI is a model of sensorimotor gating, which is deficient in schizophrenia and other mental illnesses," explained A. Gogos and colleagues. "A total of 11 healthy women were tested following four acute treatment conditions:...
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