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Breast Cancer

Breast cancer fine needle aspiration cytology specimens contain overexpressed genes

Published in Women's Health Weekly, May 8th, 2006

Breast cancer fine needle aspiration cytology (FNAC) specimens contain overexpressed genes that can be used as diagnostic markers.

According to recent research from Japan, "Overexpression of HER2 protein and HER2 gene amplification in breast cancer are prognostic factors for the response to specific medical treatments such as trastuzumab, endocrine therapy, and chemotherapy. Whereas HER2 expression and gene amplification are generally examined in tissue sections, we investigated whether specimens from FNAC are adequate for these analyses."

"HER2 protein overexpression and HER2 gene amplification were assessed in both FNAC specimens and tissue...

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