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Cancer Mortality

Bilateral salpingo-oophorectomy reduces overall, but not cancer-specific, mortality

Published in Women's Health Weekly, May 15th, 2006

Bilateral salpingo-oophorectomy reduces overall mortality, but not cancer-specific mortality.

"Bilateral prophylactic salpingo-oophorectomy (BPSO) is used widely used to reduce the risk of breast and ovarian cancer in women with BRCA1 and BRCA2 mutations. However, the reduction in mortality after this surgery is unclear," noted scientists in the United States.

S.M. Domchek and colleagues of the University of Pennsylvania stated, "We aimed to assess whether BPSO improves overall mortality or cancer-specific mortality in BRCA1 and BRCA2 mutation carriers. We identified a prospective cohort of 666 women with...

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