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Lorus announces down regulation of GTI-2040 molecular target in breast cancer clinical study

Published in Women's Health Weekly, May 15th, 2006

Lorus Therapeutics Inc., a biopharmaceutical company focused on pharmaceutical products and technologies for managing cancer, announced publication of data demonstrating decreased expression of the molecular target for its antisense drug, GTI-2040, in a phase 2 breast cancer clinical trial.

The article, titled "Analysis of ribonucleotide reductase M2 mRNA levels in patient samples after GTI-2040 antisense drug treatment," to be published in the Oncology Reports (2006;15-5:1299-1304), presents a case study from a U.S. National Cancer Institute (NCI)-sponsored phase 2 clinical trial of GTI-2040 in combination with capecitabine in metastatic breast cancer.

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