Published in Women's Health Weekly, May 29th, 2006
Study 1: Human cancer development could be linked to somatic mutations of the ERBB4 kinase domain.
"The EGFR family consists of 4 receptor tyrosine kinases, EGFR (ERBB1), ERBB2 (HER2), ERBB3 (HER3) and ERBB4 (HER4). Recent reports revealed that the kinase domains of both EGFR (ERBB1) and ERBB2 gene were somatically mutated in human cancers, raising the possibility that the other ERBB members possess somatic mutations in human cancers," scientists in South Korea reported.
"Here, we performed mutational analysis of the ERBB4 kinase domain by...
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