Breast Cancer
Breast cancer models reveal the stage-specific effects of 2-methoxyestradiol
Published in Women's Health Weekly, June 5th, 2006
"2ME2 , a metabolite of 17-beta-estradiol, inhibits angiogenesis and has additional antitumor activities. We have analyzed the tumor stage-specific effects of 2ME2 in the C3(1)/Tag transgenic mouse model for breast cancer, which spontaneously develops estrogen receptor-negative mammary tumors following a predictable progression of lesion formation," scientists in the United States report.
"When given either as a therapeutic agent in established tumors (late intervention study) or in mice with pre-invasive mammary lesions (early...
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