Breast Cancer
Invasive micropapillary breast cancers manufacture excess VEGF-C
Published in Women's Health Weekly, June 5th, 2006
"Invasion to lymphatic vessels and metastasis to lymph nodes are frequent complications in invasive micropapillary carcinoma (IMPC) of human breast cancer. VEGF-C and its receptor, VEGFR-3 have been implicated as the important factors in the formation of lymphatic vessels and recent experimental evidence strongly suggests that lymphangiogenesis in tumor promotes lymphatic metastasis," researchers in Japan report.
Y.S. Li and colleagues of Hiroshima University said, "To clarify the mechanism of its occurrence, the expression of VEGF-C, VEGFR-3 and...
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