Breast Cancer
Most breast cancers coexpress leptin, although OBR-S is an independent prognostic factor
Published in Women's Health Weekly, June 12th, 2006
"Leptin and obesity are clearly related, and obesity is associated with an increased risk of breast cancer. We therefore measured the expression of leptin and its two main receptor isoforms, OBR-L and OBR-S, in 322 breast cancers. We analyzed their relations with the classical prognostic factors and with survival to establish their links with breast cancer," scientists in France report.
F. Revillion and colleagues at the Center Oscar Lambret explained, "The expression of leptin and its receptors was quantified by real-time reverse...
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