Breast Cancer
Clarifying link between breast cancer risk and gene-gene interactions requires larger sample sizes
Published in Women's Health Weekly, June 19th, 2006
According to recent research from the United States, "The double-strand break DNA repair pathway has been implicated in breast carcinogenesis. We evaluated the association between 19 polymorphisms in 7 genes in this pathway (XRCC2, XRCC3, BRCA2, ZNF350, BRIP1, XRCC4, LIG4) and breast cancer risk in 2 population-based studies in USA (3,368 cases and 2,880 controls) and Poland (1,995 cases and 2,296 controls)."
"These data suggested weak associations with breast cancer risk for XRCC3 T241M and IVS7-14A >G (pooled odds ratio (95% confidence...
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