Breast Cancer
Her 2/neu might be involved in the pathogenesis of Sezary syndrome
Published in Women's Health Weekly, July 6th, 2006
According to a study from Germany, "Her 2/neu gene amplification has been reported in several types of cancer. Monoclonal antibodies against the Her 2/neu receptor are used as a treatment in e.g. metastatic breast cancer."
"The aim of this study was to determine the frequency of additional Her 2/neu gene copies in relations to the number of chromosome 17 centromeres of patients with Sezary syndrome. Fluorescence in situ hybridization (FISH) with probes specific for the Her 2/neu gene locus and the centromere of chromosome 17 was performed on nuclei from peripheral blood cells of 9...
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