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Breast Cancer

Breast cancer-related sentinel lymph nodes evaluated by cytokeratin immunohistochemistry

Published in Women's Health Weekly, July 20th, 2006

Sentinel lymph nodes in breast cancer patients could be evaluated by cytokeratin immunohistochemistry (IHC).

According to recent research from Hungary, "IHC reveals a higher rate of occult lymph node metastases among lobular carcinomas than among ductal breast cancers. IHC is widely used but is seldom recommended for the evaluation of sentinel lymph nodes in breast cancer patients."

"[The study's aim was] to assess the value of cytokeratin IHC for the detection of metastases in sentinel lymph nodes of patients with invasive lobular carcinoma," explained G. Cserni and colleagues, Bacs Kiskun County Teaching Hospital. "The value of IHC, the types of...

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