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Lung Cancer

Gender differences in lung cancer may be related to nicotine metabolism in women

Published in Women's Health Weekly, July 20th, 2006

Gender differences in lung cancer may be related to the influence of sex hormones on nicotine metabolism in women.

According to investigators at the University of California, "Several studies have reported that female smokers have a higher risk of lung cancer than male smokers. This could be related to sex differences in nicotine metabolism and related smoking behavior. This study tested the hypothesis that women metabolize nicotine more rapidly than men and that, among women, oral contraceptive users metabolize nicotine more rapidly than nonusers of oral contraceptives."

"Two hundred seventy-eight healthy volunteers who were twins and 16 who were...

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