Breast Tumors
Breast tumor malignancy detected by methylation-specific PCR of RARb2 and RASSF1A genes
Published in Women's Health Weekly, July 27th, 2006
According to recent research from Russia, "Tumour development is characterised by the increased circulating DNA (cirDNA) concentration and by tumour-related changes in blood plasma DNA. Concentration of cirDNA and methylation of RARb2, RASSF1A and HIC-1 gene promoters were investigated in cell-free and cell-surface-bound fractions from healthy donors, patients with breast cancer, and patients with breast fibroadenoma."
"Tumour development was shown to lead to significant changes in the distribution of cirDNA between cell-free and cell-surface-bound...
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