Breast Cancer
Breast cancer spread is reduced upon the administration of therapy targeting protein kinase c-Src
Published in Women's Health Weekly, August 24th, 2006
According to a study from Italy, "Src is a proto-oncogene, belonging to the nonreceptor protein kinases family, which plays a prominent role in carcinogenesis. In this study, we tested the hypothesis that c-Src could promote breast cancer metastasis acting on several cell types and that pharmacological disruption of its kinase activity could be beneficial for the treatment of metastases."
"Female BALB/c-nu/nu mice were subjected to intracardiac injection of the human breast cancer cells MDA-MB-231 (MDA-231), which induced prominent bone and visceral...
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