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Obstetrics

Microarray paired with emulsions PCR is effective to detect fetal DNA in maternal plasma

Published in Women's Health Weekly, August 31st, 2006

A microarray paired with emulsions PCR is an effective method to detect fetal DNA in maternal plasma.

According to investigators at Southeast University, "The presence of fetal DNA in maternal plasma made noninvasive prenatal diagnosis possible. Although fetal DNA has been used in several genetic disease diagnoses, many challenges remained in the detection methods."

"We attempted to develop a sensitive and reliable microarray coupled with emulsions PCR method to detect the fetal DNA in the plasma of pregnant women," reported Q.Y. Ge and colleagues. "Fetal DNAs extracted from the plasma of pregnant women were amplified in emulsions, and fluorescence...

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