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Sexual & Reproductive Health

Poor pregnancy outcomes in women with chlamydia infection may be due to placental apoptosis

Published in Women's Health Weekly, September 7th, 2006

Poor pregnancy outcomes in women with chlamydia infection may be due to placental apoptosis.

According to scientists in the United States, "Intrauterine infection affects placental development and function, and subsequently may lead to complications such as preterm delivery, intrauterine growth retardation, and preeclampsia; however, the molecular mechanisms are not clearly known."

"TLRs mediate innate immune responses in placenta, and recently, TLR2-induced trophoblast apoptosis has been suggested to play a role in infection-induced preterm delivery," stated O. Equils and colleagues of the University of California. "Chlamydia trachomatis is...

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