Published in Women's Health Weekly, September 7th, 2006
Study 1: Mucosal administration of CpG oligodeoxynucleotide (ODN) elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes.
Scientists in Sweden and the United States report, "Although sexually transmitted pathogens are capable of inducing pathogen-specific immune responses, vaginal administration of nonreplicating antigens elicits only weak, nondisseminating immune responses. The present study was undertaken to examine the potential of CpG-containing...
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