Published in Women's Health Weekly, September 14th, 2006
Study 1: HER2/neu-derived peptide GP2 is promising for use in a breast cancer vaccine.
According to a study from the United States, "E75 and GP2 are human leukocyte antigen (HLA)-A2-restricted immunogenic peptides derived from the HER2/neu protein. In a E75 peptide-based vaccine trial, pre-existing immunity and epitope spreading to GP2 was detected.
"The purpose of this study was to further investigate GP2 for potential use in vaccination strategies. Importantly, a naturally occurring polymorphism (I->V at position 2, 2VGP2) associated with...
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