Obstetrics

First trimester use of NSAIDs is associated with cardiac abnormalities in babies

Published in Women's Health Weekly, September 14th, 2006

Women who take non-steroidal anti-inflammatory drugs (NSAIDs) early in their pregnancies may be more likely to give birth to babies with congenital defects, particularly cardiac septal defects. These are the findings of a case-control study published in Birth Defects Research Part B, a journal published by John Wiley & Sons.

Many pregnant women get prescriptions for NSAIDs during their first trimester, and even more-up to 15%-take over-the-counter versions of these drugs. Previous studies have shown that taking NSAIDs toward the end of a pregnancy can cause certain circulatory problems-premature closure of the ductus arteriosus and patent ductus arteriosus, but...

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Source: Women's Health Weekly (2006-09-14)

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