Breast Cancer
New findings in breast cancer described from Italy and the United States
Published in Women's Health Weekly, October 12th, 2006
Study 1: CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a TH1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory.
Scientists writing in the journal Clinical Cancer Research report, "We have shown previously that the MHC class II-negative murineTS/A adenocarcinoma is rejected in vivo if induced to express MHC class II molecules by transfection of the MHC class II transactivator CIITA. In this study, we explored the immunologic basis of tumor rejection and the correlation between histopathology of...
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