Antimicrobials
Plasmacytoid dendritic cells play key role in antiviral protection by vaginal microbicide
Published in Women's Health Weekly, October 12th, 2006
According to a study from the United States, "Topical microbicides represent a promising new approach to preventing HIV and other sexually transmitted infections. TLR agonists are ideal candidates for microbicides, as they trigger a multitude of antiviral genes effective against a broad range of viruses. Although vaginal application of CpG oligodeoxynucleotides (ODNs) and poly I:C has been shown to protect mice from genital herpes infection, the mechanism by which these agents provide protection remains unclear."
"We show that...
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