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Breast Cancer Vaccine

Virosome-based breast cancer vaccine enters clinical development

Published in Women's Health Weekly, October 26th, 2006

Pevion Biotech announced the start of phase I clinical testing of its virosome-based breast cancer vaccine. The multivalent vaccine will be tested for its safety and immunogenicity in patients overexpressing the HER-2/neu oncoprotein.

Pevion Biotech, in collaboration with Bio Life Science (Vienna), has designed a therapeutic peptide vaccine to protect breast cancer patients from tumor recurrence following treatment of the primary tumor. The vaccine uses synthetic peptide antigens originating from the HER-2/neu oncoprotein, a protein almost exclusively present on cancerous cells, specifically breast cancer cells.

The antigens were identified by Bio...

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