Apoptosis
Apoptosis is induced by valinomycin in Chinese hamster ovary cells
Published in Women's Health Weekly, November 2nd, 2006
"Accumulating evidence endorses that excessive K+ efflux is an ionic mechanism underlying apoptosis both in neuronal and non-neuronal cells. K+ channels play important roles in mediating the pro-apoptotic K+ efflux.
"CHO cells have been widely used for gene transfection experiments. These cells lack detectable endogenous voltage-gated K+ channels. We were interested in knowing whether the absence of endogenous K' channels would render wild-type CHO cells more resistant...
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