HIV/AIDS Prevention
New HIV/AIDS prevention study findings have been reported by researchers at Radboud University, Department of Clinical Pharmacy
Published in Women's Health Weekly, November 9th, 2006
Scientists discuss in "Brief report: enzyme inducers reduce elimination half-life after a single dose of nevirapine in healthy women" new findings in hiv/aids. "Single-dose nevirapine (SD-NVP) to prevent mother-to-child transmission (MTCT) of HIV is associated with development of NVP resistance, probably because of its long half-life in combination with a low genetic barrier to resistance. The objective of this study was to find enzyme inducers to reduce the NVP half-life," scientists in Nijmegen, Netherlands report.
"The design of this phase 1 pharmacokinetic study was a single-center, open-label, 2-period, 9-group study. After administration of a single 200-mg dose of...
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