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Breast Cancer Therapy

Researchers from St. Bartholomew's Hospital publish new studies and findings in the area of breast cancer therapy

Published in Women's Health Weekly, November 9th, 2006

Researchers detail in "Cyclo-oxygenase-2 (COX-2) mRNA expression and hormone receptor status in breast cancer," new data in breast cancer. According to a study from London, the United Kingdom, "The purpose of this study was to evaluate COX-2 mRNA expression with known clinical prognostic features of breast cancer, oestrogen/progesterone receptor status, tumor size and grade. Total RNA was extracted from 45 frozen breast tumor (invasive) and 22 normal breast tissue samples."

"COX-2 mRNA transcription was quantified using a real time RT-PCR assay and expressed as copy number/microg total RNA. All specimens were assessed for tumor grade, size, nodal status and presence of...

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