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Parkinson Disease

University of Medicine, Center for Neurologic Diseases describes research in parkinson disease

Published in Women's Health Weekly, November 30th, 2006

Data detailed in "Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease" have been presented. According to recent research from the United States, "There is ample biochemical, pathological, and genetic evidence that the metabolism of alpha-synuclein (alpha-syn) plays a crucial role in the pathogenesis of Parkinson disease (PD). To examine whether quantification of alpha-syn in cerebrospinal fluid (CSF) is potentially informative in the diagnosis of PD, we developed a specific ELISA system and measured the concentration of alpha-syn in CSF from 33 patients with PD (diagnosed according to UK PD Society Brain Bank criteria) and 38 control...

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