Spermatogenesis

Data on spermatogenesis discussed by investigators at Monash University, Institute of Medical Research

Published in Women's Health Weekly, December 7th, 2006

A new study, "Expression of hedgehog signalling components in adult mouse testis," is now available. According to recent research from Clayton, Australia, "Hedgehog (Hh) signalling is known to regulate many aspects of normal development as well as being upregulated in various cancers. Signalling is mediated by the Gli family of zinc finger transcription factors."

"Based on observations that deletion of one of the three Hh genes, Dhh, leads to male infertility, we hypothesized that regulated expression of Hh signalling components would be a feature of adult spermatogenesis. We used in situ hybridization to characterise Gli gene expression in juvenile and adult mouse...

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Source: Women's Health Weekly (2006-12-07)

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