Data detailed in "Relationship of the aberrant DNA hypermethylation of cancer-related genes with carcinogenesis of endometrial cancer" have been presented. According to recent research published in the journal Oncology Reports, "Epigenetic abnormalities including the aberrant DNA hypermethylation of the promoter CpG islands play a key role in the mechanism of gene inactivation in cell carcinogenesis. To identify the genes associated with aberrant DNA hypermethylation in endometrial carcinogenesis, we studied the hypermethylation of the promoter regions of five genes: hMLH1, APC, E-cadherin, RAR-beta and p16."
"The frequencies of aberrant hypermethylation were...
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