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Down Syndrome

Research data from Children's Hospital update understanding of down syndrome in children

Published in Women's Health Weekly, December 21st, 2006

New research, "Down syndrome and acute lymphoblastic leukaemia," is the subject of a report. According to recent research from the United States, "Acute lymphoblastic leukaemia in children with Down syndrome (ALL-DS) is characterised by unique clinical and biological features. Notable among these are an absence of ALL in DS patients <1 year of age; a lower incidence of favourable and unfavourable chromosomal translocations; heightened sensitivity to methotrexate; and an increased propensity to infections."

"Although children with ALL-DS have historically fared less well than their non-DS counterparts (ALL-NDS), recent data indicate that outcomes in ALL-DS are now...

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