Breast Cancer Immunology

Research in the area of breast cancer immunology reported from Tohoku University, Department of Pathology

Published in Women's Health Weekly, January 25th, 2007

Researchers detail in "Immunolocalization of liver receptor homologue-1 (LRH-1) in human breast carcinoma: possible regulator of insitu steroidogenesis," new data in breast cancer. "Liver receptor homologue-1 (LRH-1) belongs to a class of nuclear orphan receptor. We examined immunolocalization of LRH-1 in 106 breast carcinomas," scientists writing in the journal Cancer Letters report.

"LRH-1 immunoreactivity was detected in 43% of the invasive ductal carcinoma. It was negatively correlated with clinical stage, histological grade and HER2 status, and positively associated with sex-steroid receptors, steroidogenic acute regulatory protein, P450 side-chain cleavage,...

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Source: Women's Health Weekly (2007-01-25)

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