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Women's Health Weekly

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Breast Cancer Immunology



Study findings from Technical University of Munich broaden understanding of breast cancer immunology



February 1st, 2007

Scientists discuss in "Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels" new findings in breast cancer. "Insulin is a hormone crucial to metabolism and an essential growth factor for normal and neoplastic tissues. We have now determined insulin in extracts of 23 primary breast cancer specimens and of non-neoplastic breast tissues by a chemiluminescent immunoassay," investigators in Munchen, Germany report.

"Remarkably, insulin was measured only in grade 3 tumors, whereas grade 2 carcinomas and the normal mammary gland were each insulin-negative. We also...


Source: Women's Health Weekly (2007-02-01)

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