Women's Health Weekly
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Breast Cancer Therapy
New breast cancer therapy data have been reported by researchers at Technical University, Department of Internal Medicine
February 1st, 2007
Research findings, "CD8-mediated type 1 antitumor responses selectively modulate endogenous differentiated and nondifferentiated T cell localization, activation, and function in progressive breast cancer," are discussed in a new report. According to recent research published in the Journal of Immunology, "CD8 T cell-mediated immune responses fall into two distinct types based on effector cell-derived cytokine production. Type I CD8 T cells (Tc1) produce IFN-gamma, whereas type 2 cells (Tc2) secrete IL-4, IL-5, IL-10, and GM-CSF." "Using a murine TCR transgenic T cell/breast tumor model, we show that adoptively transferred Ag-specific Tc1 cells are more effective...
Source: Women's Health Weekly (2007-02-01)
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