Women's Health Weekly
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Angiogenesis
Study data from Mount Vernon Cancer Center update knowledge of angiogenesis
February 1st, 2007
New research, "The relationship of the neo-angiogenic marker, endoglin, with response to neoadjuvant chemotherapy in breast cancer," is the subject of a report. "Endoglin (CD105) is upregulated in endothelial cells of tissues undergoing neovascularisation. A greater number of CD105-positive vessels predicts poor survival in breast cancer," scientists in the United Kingdom report. "We examine whether CD105 expression predicts response to neoadjuvant chemotherapy. Fifty-seven women (median age 50 years, range 29-70) received neoadjuvant chemotherapy for operable breast cancer. Immunohistochemical staining using monoclonal antibodies to CD105 and CD34 was performed on...
Source: Women's Health Weekly (2007-02-01)
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