Women's Health Weekly
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Breast Cancer Therapy
Researchers from Ohio State University, Comprehensive Cancer Center publish new studies and findings in the area of breast cancer therapy
February 1st, 2007
Investigators publish new data in the report "Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression." According to a study from the United States, "The WWOX gene is down-regulated in breast cancer and loss of Wwox expression correlates with important clinical features of breast cancer. Thus, we have examined the effect of restoration of Wwox expression in breast cancer-derived cells." "Wwox protein expression was restored by the following: (a) infection with a recombinant adenovirus carrying WWOX cDNA (Ad-WWOX) or (b) treatment with the DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, to activate the endogenous...
Source: Women's Health Weekly (2007-02-01)
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