Women's Health Weekly
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Breast Cancer
Investigators at University College, University College of Dublin zero in on breast cancer
February 1st, 2007
A report, "Growth factor-dependent regulation of survivin by c-myc in human breast cancer," is newly published data in Journal of Molecular Endocrinology. "Survivin has emerged as a unique regulator of cell death through its response to growth factors, such as basic fibroblast growth factor (bFGF), which we have previously shown to be mitogen-activated protein kinase (MAPK) dependent. The transcriptional complex myc/max is an oncogene that lies downstream of the MAPK pathway, suggesting a possible role in survivin's regulation," scientists writing in the Journal of Molecular Endocrinology report. "In this study, we investigated the ability of bFGF to induce...
Source: Women's Health Weekly (2007-02-01)
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