Researchers from University Hospital discuss findings in ovarian cancer

New investigation results, "An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma," are detailed in a study published in Clinical Cancer Research. "Cancer of the ovary confers the worst prognosis among women with gynecologic malignancies, underscoring the need to develop new biomarkers for detection of early disease, particularly those that can be readily monitored in the blood. We developed an algorithm to identify secreted proteins encoded among approximately 22,500 genes on commercial oligonucleotide arrays and applied it to gene expression profiles of 67 stage I to IV serous papillary carcinomas and 9 crudely enriched...

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