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Angiogenesis

Reports outline angiogenesis study results from University Hospital, Faculty of Health Sciences

Published in Women's Health Weekly, March 8th, 2007

New investigation results, "Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo," are detailed in a study published in Clinical Cancer Research. "Vascular endothelial growth factor (VEGF) is a potent stimulator of angiogenesis, which is crucial in cancer progression. We have previously shown that estradiol (E2) increases VEGF in breast cancer," scientists in Sweden report.

"Phytoestrogens are potential compounds in breast cancer prevention and treatment by poorly understood mechanisms. The main phytoestrogens in Western diet are lignans, and flaxseed is a...

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