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Pharmacology

Studies from Bayer HealthCare provide new data on pharmacology

Published in Women's Health Weekly, March 15th, 2007

A report, "Body weight has limited influence on the safety, tolerability, pharmacokinetics, or pharmacodynamics of rivaroxaban (BAY 59-7939) in healthy subjects," is newly published data in Journal of Clinical Pharmacology. "Anticoagulants are often dose adjusted, or their use restricted, in patients with extremes of body weight. Rivaroxaban (BAY 59-7939) is a novel, oral, direct factor Xa inhibitor in clinical development," scientists in Wuppertal, Germany report.

"This was a randomized, single-blind, placebo-controlled, parallel-group study in healthy male and female subjects to assess the effect of extreme body weight (<or=50 kg and >120 kg), and gender, on the...

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