Breast Cancer Genetics
Research reports on breast cancer genetics from University of Washington, Department of Medicine provide new insights
Published in Women's Health Weekly, March 15th, 2007
Data detailed in "Ten genes for inherited breast cancer" have been presented. According to a study from the United States, "Inherited breast cancer is associated with germline mutations in ten different genes in pathways critical to genomic integrity. BRCA1 and BRCA2 mutations confer very high risks of breast and ovarian cancer. p53 and PTEN mutations lead to very high breast cancer risks associated with rare cancer syndromes."
"Mutations in CHEK2, ATM, NBS1, RAD50, BRIP1, and PALB2 are associated with doubling of breast cancer risks. In addition, biallelic mutations in BRCA2, BRIP1, and PALB2 cause Fanconi anemia," wrote T. Walsh and colleagues, University of...
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