Chlamydia
Study results from Umea University, Department of Molecular Biology provide new insights into chlamydia
Published in Women's Health Weekly, March 22nd, 2007
Data detailed in "Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle" have been presented. "Intracellular parasitism by Chlamydiales is a complex process involving transmission of metabolically inactive particles that differentiate, replicate, and re-differentiate within the host cell. A type three secretion system (T3SS) has been implicated in this process," investigators in Umea, Sweden report.
"We have here identified small molecules of a chemical class of acylated hydrazones of salicylaldehydes that specifically blocks the T3SS of Chlamydia. These compounds also affect the developmental cycle showing that the...
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