Human Papillomavirus Immunology
Research on human papillomavirus immunology reported by scientists at Malmo University, Department of Medical Microbiology
Published in Women's Health Weekly, April 5th, 2007
Current study results from the report, "Deletion of a major neutralizing epitope of human papillomavirus type 16 virus-like particles," have been published. According to recent research published in the Journal of General Virology, "Human papillomavirus type 16 (HPV-16) is a major cause of human cancer. Effective prophylactic vaccines are based on type-specific neutralizing antibodies."
"A major neutralizing epitope has been defined by the monoclonal antibody H16.V5. To investigate the importance of this epitope for overall immunogenicity of HPV-16, HPV-16 virus-like particles devoid of the H16.V5 epitope were engineered by site-directed mutagenesis of ten...
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