Ovarian Cancer Therapy
Investigators at Virginia Commonwealth University, Department of Chemistry target ovarian cancer therapy
Published in Women's Health Weekly, June 14th, 2007
New investigation results, "Promotion of DNA strand breaks, interstrand cross-links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes," are detailed in a study published in Biochemical Pharmacology. "Cisplatin is one of the primary drugs utilized in the treatment of ovarian cancer. However, despite the initial effectiveness of chemotherapy in suppressing this disease, drug resistance almost invariably develops and cures are relatively rare," researchers in the United States report.
"While it is generally thought that only compounds of the cis geometry express antitumor activity, a number of transplatinum...
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