Hormones
University of California, Department of Pharmacology describes research in hormones
Published in Women's Health Weekly, June 21st, 2007
Current study results from the report, "Age alters cerebrovascular inflammation and effects of estrogen," have been published. According to a study from the United States, "In young adult females, estrogen treatment suppresses the cerebrovascular inflammatory response; this is mediated in part via NF-kappaB, a key regulator of inflammatory genes. To examine whether age modifies effects of estrogen on vascular inflammation in the brain, female rats, 3 and 12 mo of age, were ovariectomized; half were treated with estrogen for 4 wk."
"Cerebral blood vessels were isolated from the animals at 4 and 13 mo of age. Inflammation was induced by LPS, either injected in vivo or...
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