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Breast Cancer

Tumor cell activity may provide clues for treating breast cancer in young women

Published in Women's Health Weekly, June 21st, 2007

When women under 50 develop breast cancer the disease tends to be more aggressive and less responsive to treatment than when it occurs in older women. Researchers at the Duke Institute for Genome Sciences & Policy and the Duke University Comprehensive Cancer Center may have discovered a part of the reason why, and their findings may lead to targeted therapies that can help treat patients more effectively.

The researchers discovered that the tumors found in women under the age of 45 have certain patterns of cellular activity that confer a poorer prognosis in younger women, while the same tumor cell activity in older women confers a better prognosis, demonstrating the...

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