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Epilepsy Therapy

Studies from University Hospital, Department of Neurology provide new data on epilepsy therapy

Published in Women's Health Weekly, August 2nd, 2007

Investigators publish new data in the report "Folate status in women of childbearing age with epilepsy. Treatment with cytochrome P450 enzyme-inducing antiepileptic drugs (P450-inducing AEDs) is known to interfere with folate metabolism. Low folate status is of special concern in women with epilepsy who might become pregnant," investigators in Norway report.

"Therefore, folate status was assessed in women age 16-42 treated for epilepsy. Staple food is not folic acid fortified in Norway. Only 1/94 women was folate-deficient by the laboratory reference value for serum folate of >4 nM. Fourteen (15%) patients with serum folate values from 5 to 9 nM may be considered...

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