Breast Cancer
Scientists at National Cheng-Kung University, Department of Radiation Oncology release new data on breast cancer
Published in Women's Health Weekly, August 2nd, 2007
Research findings, "Hypoxia-inducible factor-1alpha correlates with MET and metastasis in node-negative breast cancer," are discussed in a new report. According to a study from Tainan, Taiwan, "The mechanism of tumor hypoxia promoting metastasis remains uncertain. Hypoxia-inducible factor-1alpha (HIF-1alpha) is a key mediator of the cellular response to hypoxia and binds the met promoter, resulting in increased expression of MET."
"In breast cancer, MET overexpression is associated with death caused by metastatic disease. Aim of this study is to investigate the role of HIF-1alpha in MET expression and metastasis in lymph node negative breast cancer. We recruited a...
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