Ovarian Cancer
Reports from Zhejiang University describe recent advances in ovarian cancer
Published in Women's Health Weekly, August 23rd, 2007
New investigation results, "Human ovarian carcinoma cells generate CD4(+)CD25(+) regulatory T cells from peripheral CD4(+)CD25(-) T cells through secreting TGF-beta," are detailed in a study published in Cancer Letters. "Increased CD4(+)CD25(+) regulatory T cells predicted poor prognosis in ovarian carcinoma patients. This study aimed to define whether soluble substances secreted by ovarian carcinoma could up-regulate the proportion of CD4(+)CD25(+) regulatory T cells," scientists in Hangzhou, People's Republic of China report.
"Similar to TGF-beta, the low MWF (<50kDa) of supernatant derived from SKOV3 could convert part of freshly isolated CD4(+)CD25(-) T...
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